Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014018
| Cat. No. | CDFR014018 |
| Description | NativeORF clone of Rattus norvegicus dyskeratosis congenita 1, dyskerin (Dkc1) as transfection-ready DNA NM_133419.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Dkc1 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | DKC1 |
| Background | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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