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Rat Dgkg cDNA Clone(NM_013126.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010925

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Gene Information

Cat. No. CDFR010925
Description NativeORF clone of Rattus norvegicus diacylglycerol kinase, gamma (Dgkg) as transfection-ready DNA NM_013126.1
Product Type cDAN Clone
Gene Abbr Dgkg
Species Rat
Vector pCMV6Entry
Target Gene DGKG
Background This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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