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Rat Dennd5a cDNA Clone(NM_001107546.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007232

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Gene Information

Cat. No. CDFR007232
Description NativeORF clone of Rattus norvegicus DENN/MADD domain containing 5A (Dennd5a) as transfection-ready DNA NM_001107546.2
Product Type cDAN Clone
Gene Abbr Dennd5a
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene DENND5A
Background This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
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