Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR007232
| Cat. No. | CDFR007232 |
| Description | NativeORF clone of Rattus norvegicus DENN/MADD domain containing 5A (Dennd5a) as transfection-ready DNA NM_001107546.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Dennd5a |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | DENND5A |
| Background | This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017] |
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