Rat Dctn2 cDNA Clone(NM_001004239.1)

Name: Rat Dctn2 cDNA Clone(NM_001004239.1)
SKU: CDFR001386
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001386

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Product Information

Gene Information

Cat. No.	CDFR001386
Description	NativeORF clone of Rattus norvegicus dynactin 2 (Dctn2) as transfection-ready DNA NM_001004239.1
Product Type	cDAN Clone
Gene Abbr	Dctn2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

DCTN2

Background

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]

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