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Rat Dazap1 cDNA Clone(NM_001025742.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003882

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Gene Information

Cat. No. CDFR003882
Description NativeORF clone of Rattus norvegicus DAZ associated protein 1 (Dazap1) as transfection-ready DNA NM_001025742.1
Product Type cDAN Clone
Gene Abbr Dazap1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene DAZAP1
Background In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
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