Rat Daxx cDNA Clone(NM_080891.2)

Name: Rat Daxx cDNA Clone(NM_080891.2)
SKU: CDFR013854
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013854

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Product Information

Gene Information

Cat. No.	CDFR013854
Description	NativeORF clone of Rattus norvegicus death-domain associated protein (Daxx) as transfection-ready DNA NM_080891.2
Product Type	cDAN Clone
Gene Abbr	Daxx
Species	Rat
Vector	pCMV6Entry

Target Gene

DAXX

Background

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

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