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Rat D2hgdh cDNA Clone(NM_001106926.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006280

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Gene Information

Cat. No. CDFR006280
Description NativeORF clone of Rattus norvegicus D-2-hydroxyglutarate dehydrogenase (D2hgdh), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001106926.1
Product Type cDAN Clone
Gene Abbr D2hgdh
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene D2HGDH
Background This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. [provided by RefSeq, Jul 2008]
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