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Rat Cyth3 cDNA Clone(NM_053912.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013626

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Gene Information

Cat. No. CDFR013626
Description NativeORF clone of Rattus norvegicus cytohesin 3 (Cyth3) as transfection-ready DNA NM_053912.2
Product Type cDAN Clone
Gene Abbr Cyth3
Species Rat
Vector pCMV6Entry
Target Gene CYTH3
Background This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]
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