Rat Cyth2 cDNA Clone(NM_053911.2)

Name: Rat Cyth2 cDNA Clone(NM_053911.2)
SKU: CDFR013625
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013625

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Product Information

Gene Information

Cat. No.	CDFR013625
Description	NativeORF clone of Rattus norvegicus cytohesin 2 (Cyth2) as transfection-ready DNA NM_053911.2
Product Type	cDAN Clone
Gene Abbr	Cyth2
Species	Rat
Vector	pCMV6Entry

Target Gene

CYTH2

Background

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

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