Rat Cyth1 cDNA Clone(NM_053910.1)

Name: Rat Cyth1 cDNA Clone(NM_053910.1)
SKU: CDFR013624
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013624

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Product Information

Gene Information

Cat. No.	CDFR013624
Description	NativeORF clone of Rattus norvegicus cytohesin 1 (Cyth1) as transfection-ready DNA NM_053910.1
Product Type	cDAN Clone
Gene Abbr	Cyth1
Species	Rat
Vector	pCMV6Entry

Target Gene

CYTH1

Background

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

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