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Rat Cyp26b1 cDNA Clone(NM_181087.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014937

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Gene Information

Cat. No. CDFR014937
Description NativeORF clone of Rattus norvegicus cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1) as transfection-ready DNA NM_181087.2
Product Type cDAN Clone
Gene Abbr Cyp26b1
Species Rat
Vector pCMV6Entry
Target Gene CYP26B1
Background This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
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