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Rat Cyp11b1 cDNA Clone(NM_012537.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010358

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Gene Information

Cat. No. CDFR010358
Description NativeORF clone of Rattus norvegicus cytochrome P450, subfamily 11B, polypeptide 1 (Cyp11b1), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_012537.3
Product Type cDAN Clone
Gene Abbr Cyp11b1
Species Rat
Vector pCMV6Entry
Target Gene CYP11B1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
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