Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR011801
| Cat. No. | CDFR011801 |
| Description | NativeORF clone of Rattus norvegicus cortactin (Cttn) as transfection-ready DNA NM_021868.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Cttn |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | CTTN |
| Background | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
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