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Rat Csta cDNA Clone(NM_001105876.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005606

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Gene Information

Cat. No. CDFR005606
Description NativeORF clone of Rattus norvegicus cystatin A (stefin A) (Csta) as transfection-ready DNA NM_001105876.1
Product Type cDAN Clone
Gene Abbr Csta
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CSTA
Background The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]
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