Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR008200
| Cat. No. | CDFR008200 |
| Description | NativeORF clone of Rattus norvegicus chromosome segregation 1-like (S. cerevisiae) (Cse1l) as transfection-ready DNA NM_001108607.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Cse1l |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | CSE1L |
| Background | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
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