Rat Crtc2 cDNA Clone(NM_001033895.1)

Name: Rat Crtc2 cDNA Clone(NM_001033895.1)
SKU: CDFR003898
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003898

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Product Information

Gene Information

Cat. No.	CDFR003898
Description	NativeORF clone of Rattus norvegicus CREB regulated transcription coactivator 2 (Crtc2) as transfection-ready DNA NM_001033895.1
Product Type	cDAN Clone
Gene Abbr	Crtc2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

CRTC2

Background

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

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