Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR011394
| Cat. No. | CDFR011394 |
| Description | NativeORF clone of Rattus norvegicus v-crk sarcoma virus CT10 oncogene homolog (avian) (Crk) as transfection-ready DNA NM_019302.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Crk |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | CRK |
| Background | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008] |
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