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Rat Crh cDNA Clone(NM_031019.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012495

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Gene Information

Cat. No. CDFR012495
Description NativeORF clone of Rattus norvegicus corticotropin releasing hormone (Crh) as transfection-ready DNA NM_031019.1
Product Type cDAN Clone
Gene Abbr Crh
Species Rat
Vector pCMV6Entry
Target Gene Crh
Background This gene encodes a member of the corticotropin-releasing factor family and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a neuropeptide hormone that binds to the corticotropin releasing hormone receptors (CRHR1 and CRHR2) to stimulate the release of adrenocorticotropic hormone from the pituitary gland in response to stress. The encoded protein may also regulate angiogenesis and inflammation. Homozygous knockout mice for this gene exhibit reduced corticosterone levels while the offspring of these mice die perinatally. [provided by RefSeq, Aug 2015]
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