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Rat Cpn1 cDNA Clone(NM_053526.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013251

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Gene Information

Cat. No. CDFR013251
Description NativeORF clone of Rattus norvegicus carboxypeptidase N, polypeptide 1 (Cpn1) as transfection-ready DNA NM_053526.2
Product Type cDAN Clone
Gene Abbr Cpn1
Species Rat
Vector pCMV6Entry
Target Gene CPN1
Background Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
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