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Rat Coq2 ORF Clone(NM_001044255.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371492

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Gene Information

Cat. No. CDCR371492
Product Type ORF Clone
Gene Abbr Coq2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1125 bp
Vector pCMV6-Entry
Target Gene COQ2
Background This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
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