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Rat Copa cDNA Clone(NM_001134540.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009861

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Gene Information

Cat. No. CDFR009861
Description NativeORF clone of Rattus norvegicus coatomer protein complex subunit alpha (Copa) as transfection-ready DNA NM_001134540.1
Product Type cDAN Clone
Gene Abbr Copa
Species Rat
Vector pCMV6Entry
Target Gene COPA
Background In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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