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Rat Col17a1 cDNA Clone(NM_001106366.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006105

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Gene Information

Cat. No. CDFR006105
Description NativeORF clone of Rattus norvegicus collagen, type XVII, alpha 1 (Col17a1) as transfection-ready DNA NM_001106366.1
Product Type cDAN Clone
Gene Abbr Col17a1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene COL17A1
Background This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
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