Rat Clk2 cDNA Clone(NM_001014254.1)

Name: Rat Clk2 cDNA Clone(NM_001014254.1)
SKU: CDFR003363
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003363

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Product Information

Gene Information

Cat. No.	CDFR003363
Description	NativeORF clone of Rattus norvegicus CDC-like kinase 2 (Clk2) as transfection-ready DNA NM_001014254.1
Product Type	cDAN Clone
Gene Abbr	Clk2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

CLK2

Background

This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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