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Rat Cldn7 cDNA Clone(NM_031702.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012838

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Gene Information

Cat. No. CDFR012838
Description NativeORF clone of Rattus norvegicus claudin 7 (Cldn7) as transfection-ready DNA NM_031702.1
Product Type cDAN Clone
Gene Abbr Cldn7
Species Rat
Vector pCMV6Entry
Target Gene CLDN7
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
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