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Rat Cldn10 cDNA Clone(NM_001106058.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005830

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Gene Information

Cat. No. CDFR005830
Description NativeORF clone of Rattus norvegicus claudin 10 (Cldn10) as transfection-ready DNA NM_001106058.1
Product Type cDAN Clone
Gene Abbr Cldn10
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CLDN10
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010]
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