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Rat Clcn4 cDNA Clone(NM_022198.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011885

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Gene Information

Cat. No. CDFR011885
Description NativeORF clone of Rattus norvegicus chloride channel 4-2 (Clcn4-2) as transfection-ready DNA NM_022198.2
Product Type cDAN Clone
Gene Abbr Clcn4
Species Rat
Vector pCMV6Entry
Target Gene CLCN4
Background The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012]
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