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Rat Chst8 ORF Clone(NM_001107504.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR374244

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Gene Information

Cat. No. CDCR374244
Product Type ORF Clone
Gene Abbr Chst8
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1254 bp
Vector pCMV6-Entry
Target Gene CHST8
Background The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
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