Rat Chp2 cDNA Clone(NM_182738.1)

Name: Rat Chp2 cDNA Clone(NM_182738.1)
SKU: CDFR015025
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR015025

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Product Information

Gene Information

Cat. No.	CDFR015025
Description	NativeORF clone of Rattus norvegicus calcineurin B homologous protein 2 (Chp2) as transfection-ready DNA NM_182738.1
Product Type	cDAN Clone
Gene Abbr	Chp2
Species	Rat
Vector	pCMV6Entry

Target Gene

CHP2

Background

This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013]

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