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Rat Chn2 cDNA Clone(NM_032084.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012435

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Gene Information

Cat. No. CDFR012435
Description NativeORF clone of Rattus norvegicus chimerin (chimaerin) 2 (Chn2) as transfection-ready DNA NM_032084.1
Product Type cDAN Clone
Gene Abbr Chn2
Species Rat
Vector pCMV6Entry
Target Gene CHN2
Background This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]
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