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Rat Chmp5 ORF Clone(NM_001025410.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR370938

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Gene Information

Cat. No. CDCR370938
Product Type ORF Clone
Gene Abbr Chmp5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 660 bp
Vector pCMV6-Entry
Target Gene CHMP5
Background CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
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