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Rat Cfhr1 cDNA Clone(NM_001044227.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004752

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Gene Information

Cat. No. CDFR004752
Description NativeORF clone of Rattus norvegicus complement component factor h-like 1 (Cfhl1) as transfection-ready DNA NM_001044227.1
Product Type cDAN Clone
Gene Abbr Cfhr1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CFHR1
Background This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
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