Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR377220
| Cat. No. | CDCR377220 |
| Product Type | ORF Clone |
| Gene Abbr | Cep290 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 7440 bp |
| Vector | pCMV6-Entry |
| Target Gene | CEP290 |
| Background | This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008] |
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