Rat Cenpj cDNA Clone(NM_001107265.1)

Name: Rat Cenpj cDNA Clone(NM_001107265.1)
SKU: CDFR006986
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR006986

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Product Information

Gene Information

Cat. No.	CDFR006986
Description	NativeORF clone of Rattus norvegicus centromere protein J (Cenpj) as transfection-ready DNA NM_001107265.1
Product Type	cDAN Clone
Gene Abbr	Cenpj
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

CENPJ

Background

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

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