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Rat Cenpa ORF Clone(NM_001106711.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373457

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Product Information

Gene Information

Cat. No. CDCR373457
Product Type ORF Clone
Gene Abbr Cenpa
Species Rat
Tag C-terminal Myc-DDK
ORF Size 480 bp
Vector pCMV6-Entry
Target Gene CENPA
Background Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]
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