Rat Cela3b cDNA Clone(NM_001106692.1)

Name: Rat Cela3b cDNA Clone(NM_001106692.1)
SKU: CDFR006443
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR006443

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Product Information

Gene Information

Cat. No.	CDFR006443
Description	NativeORF clone of Rattus norvegicus elastase 3B, pancreatic (Ela3b) as transfection-ready DNA NM_001106692.1
Product Type	cDAN Clone
Gene Abbr	Cela3b
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

CELA3B

Background

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009]

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