Rat Cdh8 ORF clone(NM_053393.2)

Name: Rat Cdh8 ORF clone(NM_053393.2)
SKU: CDCL183495
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL183495

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Product Information

Gene Information

Cat. No.	CDCL183495
Description	ORF Clone of Rattus norvegicus cadherin 8 DNA.
Product Type	ORF clone
Gene Abbr	Cdh8
Species	Rat
ORF Size	2400bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

CDH8

Background

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008]

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