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Rat Cdc45 cDNA Clone(NM_001105866.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005594

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Gene Information

Cat. No. CDFR005594
Description NativeORF clone of Rattus norvegicus CDC45 cell division cycle 45-like (S. cerevisiae) (Cdc45l) as transfection-ready DNA NM_001105866.2
Product Type cDAN Clone
Gene Abbr Cdc45
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CDC45
Background The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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