Rat Cdc42 cDNA Clone(NM_171994.4)

Name: Rat Cdc42 cDNA Clone(NM_171994.4)
SKU: CDFR014690
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014690

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Product Information

Gene Information

Cat. No.	CDFR014690
Description	NativeORF clone of Rattus norvegicus cell division cycle 42 (GTP binding protein) (Cdc42) as transfection-ready DNA NM_171994.4
Product Type	cDAN Clone
Gene Abbr	Cdc42
Species	Rat
Vector	pCMV6Entry

Target Gene

CDC42

Background

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]

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