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Rat Cdc25b ORF Clone(NM_133572.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR381144

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Product Information

Gene Information

Cat. No. CDCR381144
Product Type ORF Clone
Gene Abbr Cdc25b
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1725 bp
Vector pCMV6-Entry
Target Gene CDC25B
Background CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
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