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Rat Cdc14b cDNA Clone(NM_001108404.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008023

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Gene Information

Cat. No. CDFR008023
Description NativeORF clone of Rattus norvegicus CDC14 cell division cycle 14 homolog B (S. cerevisiae) (Cdc14b) as transfection-ready DNA NM_001108404.1
Product Type cDAN Clone
Gene Abbr Cdc14b
Species Rat
Vector pCMV6Entry
Target Gene CDC14B
Background The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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