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Rat Cdc14a cDNA Clone(NM_001107718.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007361

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Gene Information

Cat. No. CDFR007361
Description NativeORF clone of Rattus norvegicus CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), transcript variant 2 as transfection-ready DNA NM_001107718.2
Product Type cDAN Clone
Gene Abbr Cdc14a
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CDC14A
Background The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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