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Rat Cd3d cDNA Clone(NM_013169.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010966

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Gene Information

Cat. No. CDFR010966
Description NativeORF clone of Rattus norvegicus CD3 molecule delta polypeptide (Cd3d) as transfection-ready DNA NM_013169.1
Product Type cDAN Clone
Gene Abbr Cd3d
Species Rat
Target Gene CD3D
Background The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
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