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Rat Cct5 ORF Clone(NM_001004078.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR368317

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Gene Information

Cat. No. CDCR368317
Product Type ORF Clone
Gene Abbr Cct5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1626 bp
Vector pCMV6-Entry
Target Gene CCT5
Background The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
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