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Rat Ccnt2 ORF Clone(NM_001107171.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373896

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Gene Information

Cat. No. CDCR373896
Product Type ORF Clone
Gene Abbr Ccnt2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2169 bp
Vector pCMV6-Entry
Target Gene CCNT2
Background The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
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