Rat Ccnh ORF Clone(NM_052981.2)

Name: Rat Ccnh ORF Clone(NM_052981.2)
SKU: CDCR380089
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR380089

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Product Information

Gene Information

Cat. No.	CDCR380089
Product Type	ORF Clone
Gene Abbr	Ccnh
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	972 bp
Vector	pCMV6-Entry

Target Gene

CCNH

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]

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