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Rat Cbx5 ORF Clone(NM_001106797.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373536

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Product Information

Gene Information

Cat. No. CDCR373536
Product Type ORF Clone
Gene Abbr Cbx5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 576 bp
Vector pCMV6-Entry
Target Gene CBX5
Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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