Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR010199
| Cat. No. | CDFR010199 |
| Description | NativeORF clone of Rattus norvegicus cystathionine beta synthase (Cbs) as transfection-ready DNA NM_012522.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Cbs |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | CBS |
| Background | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016] |
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