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Rat Cav2 ORF Clone(NM_131914.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380992

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Product Information

Gene Information

Cat. No. CDCR380992
Product Type ORF Clone
Gene Abbr Cav2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 489 bp
Vector pCMV6-Entry
Target Gene CAV2
Background The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]
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