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Rat Cast ORF Clone(NM_001033716.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371289

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Product Information

Gene Information

Cat. No. CDCR371289
Product Type ORF Clone
Gene Abbr Cast
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1959 bp
Vector pCMV6-Entry
Target Gene CAST
Background The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
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