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Rat Capn3 cDNA Clone(NM_017117.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011171

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Gene Information

Cat. No. CDFR011171
Description NativeORF clone of Rattus norvegicus calpain 3 (Capn3) as transfection-ready DNA NM_017117.1
Product Type cDAN Clone
Gene Abbr Capn3
Species Rat
Vector pCMV6Entry
Target Gene CAPN3
Background Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
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